Myeloid sarcoma arising in malignant phyllodes tumour: clonal relationships revealed by comparative genome-wide analyses
نویسندگان
چکیده
منابع مشابه
Giant Malignant Phyllodes Tumour of Breast
The term phyllodes tumour includes lesions ranging from completely benign tumours to malignant sarcomas. Clinically phyllodes tumours are smooth, rounded, and usually painless multinodular lesions indistinguishable from fibroadenomas. Percentage of phyllodes tumour classified as malignant ranges from 23% to 50%. We report a case of second largest phyllodes tumour in a 35-year-old lady who prese...
متن کاملMalignant phyllodes tumour of the breast.
BACKGROUND Malignant Phyllodes Tumour (MPT) is considered to be a rare disease of the breast. The most frequent clinical presentation of a MPT is a rapidly growing breast lump. METHODS Consecutive cases of MPT registered between Jan 1, 1995 and Dec 31, 2012 at the Shaukat Khanum Memorial Cancer Hospital and Research Centre, Lahore, Pakistan, were reviewed, to obtain information on age, tumour...
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Sarcomas are thought to originate from mes-enchymal tissue, and account for 1% of adult solid malignancies and over 20% of pediatric solid malignances. Nearly 11,000 people in the USA and 200,000 people in the world will be diagnosed with sarcomas each year [101]. When they metastasize, sarcomas typically have a very poor outcome. Unlike other types of tumors, the molecular basis and accompanyi...
متن کاملGenome-wide analyses of avian sarcoma virus integration sites.
The chromosomal features that influence retroviral integration site selection are not well understood. Here, we report the mapping of 226 avian sarcoma virus (ASV) integration sites in the human genome. The results show that the sites are distributed over all chromosomes, and no global bias for integration site selection was detected. However, RNA polymerase II transcription units (protein-enco...
متن کاملMalignant phyllodes tumour as an intracystic growth with osteosarcomatous differentiation.
Phyllodes tumour is an uncommon fibro epithelial tumour of breast that often presents clinically as a rapidly enlarging lump. On mammography it appears as a soft tissue density well circumscribed mass. Ultrasound shows it to be a solid hypoechoic mass with small cystic spaces. A case of malignant phyllodes tumour with an atypical appearance of intracystic tumour on sonography is reported with p...
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ژورنال
عنوان ژورنال: British Journal of Haematology
سال: 2017
ISSN: 0007-1048
DOI: 10.1111/bjh.14539